Spatiotemporal variations, health risk assessment, and sources of potentially toxic elements in potamic water of the Anday Stream Basin (Türkiye), Black Sea Region.

Monitoring and protecting freshwater habitats are paramount for a sustainable water management perspective. This study investigated potentially toxic elements (PTEs) in the potamic water of the Anday Stream Basin (Türkiye), Black Sea Region, for a hydrological year (from May 2020 to April 2021). Among PTEs, the highest average values were recorded for sodium (Na) at 41.3 mg/L and the lowest for mercury (Hg) at 0.009 µg/L and noted under quality guidelines. The stream was found to be at the level of "Low Heavy Metal Pollution" and "Low Contamination" based on the ecotoxicological risk indices. The highest calculated hazard quotient (HQ) value of 1.21E-02 for Cd was noted in the children via the dermal pathway and the lowest of 6.91E-06 for Fe in adults via the ingestion pathway. Results revealed a higher hazard index (HI) value of 1.50E-02 for Cd to children and the lowest of 1.98E-05 for Fe to adults. As a result of applying agricultural risk indices, the stream showed sodium adsorption ratio values less than 6 and was found to be "Excellent" for agriculture. However, the sodium percentage values were less than 20 and found "Permissible" and the magnesium hazard > 50 and noted as "Unsuitable" for agriculture. Statistical analysis revealed that natural factors mainly attributed to PTE contamination of the Anday Stream Basin.

Evaluation of irrigation, drinking, and risk indices for water quality parameters of alpine lakes.

Alpine lakes are aquatic ecosystems that maintain and regulate water supply for the downstream streams, rivers, and other reservoirs. This study examined the water characteristics of various alpine lakes in Gilgit-Baltistan, Northern Pakistan. For this purpose, water was sampled and investigated for basic parameters, anions, and cations using the multi-parameter analyzers and atomic absorption spectrophotometer. Physicochemical parameters of alpine lakes were noted under the World Health Organization water guidelines, except for fluoride (F-) and turbidity in 4.3% and 36% of samples, respectively. Water quality index (WQI) classified samples (93%) as excellent and good quality (7%). Results showed maximum chronic daily intake values (0.14 ± 0.01 mg/kg-day) for nitrate (NO3-) and hazard quotient (0.80 ± 0.24) for F- in children via water intake from Upper Kachura and Shausar Lakes, respectively. Statistical analyses of Piper and Gibbs's plots revealed that the water quality is mainly characterized by bedrock geology.

Temporal variation of water quality parameters in the lacustrine of the Thrace Region, Northwest Türkiye.

Thrace is a part of the Marmara Region northwest of Türkiye. This region hosts several lentic ecosystems used for irrigation and drinking water supply. The present study was conducted to analyze the temporal distributions of water quality parameters (WQPs) of lentic ecosystems (lacustrine habitats), including lakes (L1-L2), reservoirs (R1-R12), and ponds (P1-P19) of the Thrace Region. Thirty-three lacustrine habitats were identified in the region. Freshwaters were collected in the wet (end of winter) and dry (end of summer) seasons of 2021-2022 and tested for 12 WQPs. Data was evaluated for the water quality index (WQI) and nutrient pollution index (NPI) and their overall quality level. For the evaluation of non-carcinogenic health risk indices of WQPs, the chronic daily index (CDI), hazard quotient (HQ), and hazard index (HI) were applied. Cluster analysis (CA), Pearson correlation index (PCI), and principal component analysis (PCA) were used to classify the lacustrine habitats and identify the source of WQPs. The average values were as follows: 9.28 mg/L for dissolved oxygen (DO), 94.6% for oxygen (O2) saturation, 9.29 for pH, 613 µS/cm for electrical conductivity (EC), 3.96 NTU for turbidity, 358 mg/L for total dissolved solids (TDS), 3.17 mg/L for nitrate (NO3), 0.05 mg/L for nitrite (NO2), 1.01 mg/L for phosphate (PO4), 78.5 mg/L for sulfate (SO4), and 102 mg/L for chloride (Cl). Results showed a significant increase in WQPs, including NO3, NO2, and PO4, in the wet season, while the salinity decreased from the dry to wet season. Results revealed that HI values of water contaminants in lacustrine habitats were noted to be less than one. Based on determined WQPs, the present study recommends using lacustrine water habitats for irrigation, drinking, and other domestic and industrial purposes.

Industrial wastewater irrigation increased higher heavy metals uptake and expansins, metacaspases, and cystatin genes expression in Parthenium and maize.

Industrial wastewater irrigation of agricultural crops can cause a lot of environmental and health problems in developing countries due to heavy metals deposition in agricultural soils as well as edible plant consumption by human beings. Therefore, this study was conducted to find out the heavy metals concentration in industrial wastewater and soil irrigated with that wastewater. In addition, the aim was to determine the impact of industrial wastewater irrigation on Parthenium hysterophorus and Zea mays genes involved in growth improvement and inhibition. For this purpose, plant samples from agriculture fields irrigated with wastewater from Hattar Industrial Estate (HIE) of Haripur, Pakistan, and control plants from non-contaminated soil irrigated with tape water were collected after 15 and 45 days of germination. Heavy metals concentration in the collected plant samples, wastewater, and soil was determined. The results revealed that the soil of the sample collection site was predominantly contaminated with Cr, Pb, Ni, Cu, Co, Zn, and Cd up to the concentrations of 38.98, 21.14, 46.01, 155.73, 12.50, 68.50, and 7.01 mg/kg, respectively. The concentrations of these heavy metals were found to surpass the permissible limit in normal agricultural soil. Expansins, cystatins (plant growth enhancers), and metacaspases (plant growth inhibitor) gene expression were studied through reverse transcription polymerase chain reaction. The results showed that the expression of these genes was higher in samples collected from wastewater-irrigated soils as compared to control. The expression of these genes was observed in 45 days old samples, 15 days old samples, and control. Taken together, this study suggests the use of Parthenium and maize for phytoremediation and that they should not be used for eating purposes if irrigated with industrial wastewater.

Annual effective dose estimation of radon in drinking water sources of Nizampur basin, North Western Pakistan.

This study assessed radon (222Rn) levels in drinking water sources in the Nizampur basin and their potential health risks for the local community. We analyzed 48 water samples on-site using RAD7. Additionally, we measured pH, temperature (T), total dissolved solids (TDS), redox potential (ORP), and electrical conductivity (EC) with a multiparameter analyzer. Results showed pH, T, TDS, ORP, and EC ranging from 7.2 to 8, 17 to 26 °C, 333 to 1130 mg/l, -56 to 284 mV, and 469 to 2370 µS/cm. 222Rn levels varied significantly (0.7-107 Bq/l, mean 23 ± 21, median = 17 Bq/l), with about 65 % exceeding the EPA's limit of 11.1 Bq/l, indicating health risks likely due to local geological conditions. The annual effective doses for ingestion (EwIng) were 0.87 ± 0.01, 0.35 ± 0.006, and 0.13 ± 0.002 µSv/a for adults, infants, and children, respectively. Exposure risk via the inhalation (EwInh) route ranged from 1.75 to 270 µSv/a, with the highest risk in infants, followed by children and adults. Inhalation was the primary exposure route for all age groups. Further, spatial distribution maps and hotspot analysis suggested that the central region characterized by high structural deformation and favorable geology for radon emanation was the area of concern in terms of health risks.

Spatial distribution of potentially toxic elements contaminations and risk indices of water and sediments in the Darband and Samana streams, Pakistan.

This study examined potentially toxic elements (PTE) of water and sediments in the Darband and Samana streams of Hangu District. Darband and Samana streams are the main fluvial ecosystems of Hangu District, Pakistan, directly or indirectly affecting more than 0.52 Million people. Water and sediment samples were collected and analyzed for PTE utilizing inductively coupled plasma mass spectrometry (ICP-MS). Water characteristics of Darband and Samana streams were noted within the WHO drinking water guidelines, except for Turbidity and sulfate. Most water characteristics showed higher values in the Samana stream than in the Darband stream. Similarly, most of PTE showed higher concentrations in sediments collected from the Samana stream than the Darband stream. For ecological risk evaluation, several pollution indices were employed to assess the eco-toxicological consequences. The highest contamination factor (CF) value of 15 and 20 were exhibited by molybdenum (Mo) in the Samana and Darband streams showing very high contamination. Similarly, the pollution load index (PLI) showed that 24% of the sediment samples were polluted (PLI > 1). Furthermore, a high ecological risk in a range of 160 < ERI < 320 was observed for Mo, while a low ecological risk ERI < 40 was by As for the Darband and Samana streams sediments. Statistical techniques revealed that various anthropogenic sources primarily contaminated in water and sediment. Therefore, this study recommends regular monitoring PTE contaminations in the area to avoid any health hazards in the future.

Spatial and temporal distribution of heavy metals pollution and risk indices in surface sediments of Gomal Zam Dam Basin, Pakistan.

Sediments were considered a sink and potential source of heavy metals in the aquatic system. For this purpose, the present study examined surface sediments for spatial and temporal variation of heavy metals pollution and risk indices in the Gomal Zam Dam Basin (GZDB), Pakistan. Sediment samples (n = 20) were collected from the GZDB, i.e., Gomal Zam Dam, its inlets, and outlets in the winter and summer seasons of 2020, and examined for heavy metals such as zinc (Zn), nickel (Ni), manganese (Mn), lead (Pb), chromium (Cr), copper (Cu), iron (Fe), and cobalt (Co) concentrations. Among GZDB, results showed that the Zhob River Inlet had a higher levels of heavy metals in both seasons. The results revealed that pollution load index values were < 1, observing no pollution in the aquatic system. The risk indices values revealed that sampling sites showed no or very low risk during the summer, 84% of samples showed no or very low risk during the winter, and the rest noted with reasonable risks. Winter season showed higher average values of contamination and risk indices than summer. Statistical analyses revealed that the heavy metals contaminations were mainly due to geogenic sources of rock weathering and ore deposits, with minor contributions from anthropic activities. This study recommends regular monitoring of temporal studies on heavy metals contamination in the water of the GZDB.

Ecotoxicological evaluation of organic contamination in the world's two significant gateways to the Black Sea using GIS techniques: Turkish Straits.

This study was carried out to determine the spatial-temporal distributions of limnological parameters of Çanakkale Strait (ÇS) and Istanbul Strait (IS), Turkiye. Fluvial (n = 11) and lacustrine (n = 4) habitats water samples were collected in the dry and rainy seasons of 2022-2023. Among limnological parameters, the highest mean electrical conductivity values of 6063 µS/cm were noted in the IS basin during the rainy season and the lowest was 0.04 mg/L for nitrite in the ÇS basin. Generally, the levels of organic contaminants and ecological risk indices were as follows: rivers of IS > rivers of ÇS > Alibey Dam Lake (IS) > Atikhisar Dam Lake (ÇS). The highest non-carcinogenic health risks of 0.88 were noted for children in the ÇS basin during the dry season and the lowest of <0.01 in Atikhisar Dam Lake during the rainy season. Multivariate statistical techniques were applied to data to categorize investigated ecosystems and sources apportionment of contaminants and geospatial distribution.

Pollution characteristics, sources and health risks assessment of potentially hazardous elements in sediments of ten ponds in the Saros Bay region (Türkiye).

Pollution of lentic ecosystems by potentially hazardous elements (PHE) due to human activities has become a global concern. In this study, the contents of eight PHEs in the sediments of 10 most important ponds located in the Saros Bay region (Türkiye) were evaluated. The contents of PHEs in the sediments of the ponds ranged from 0.14 mg/kg for Cd to 274 mg/kg for Mn. According to the enrichment factor (EF) results, ponds P3, P8 and P9 for Cd and pond P8 for Pb showed "moderate enrichment". However, the pollution load index (PLI) results indicated that all ponds were in a "baseline contamination" state due to the combined effect of all PHEs. Similarly, based on ecological risk assessment indices, no ecological risk from PHEs was identified. In addition, Cd, Zn, As, Cr, Cu and Pb contents in all ponds were found below threshold effect concentrations. The results of the health risk assessment indicated that non-carcinogenic and carcinogenic risks were not expected for recreational receptors due to exposure to the PHEs in the sediments via incidental ingestion and dermal contact. Correlation and cluster analysis results indicated that although agricultural activities contributed slightly to the As content, all PHEs mainly originated from natural sources.

Spatial distribution of radon contamination in hot springs water and its cancer and non-cancer risks in the Hunza-Nagar valley, Pakistan.

Radon (222Rn) is a ubiquitous radioactive gas and could threaten human life due to its potential for cancer and non-cancer risks. This study examined the measurement of 222Rn concentration and associated health risks in the hot springs of Hunza-Nagar valley. For this purpose, the hot springs water of Hunza and Nagar districts and the background sites were analyzed for 222Rn concentration using the RAD7 detector (Durridge Company, USA). The average concentrations of 222Rn were 46.1 ± 0.94, 65.3 ± 0.45, and 5.47 ± 0.25 Bq/L in the Hunza district, Nagar district, and background sites, respectively. Results showed that 222Rn concentrations of hot springs water were multifold higher than the background sites. 222Rn concentrations for hot springs water in Hunza-Nagar valley had surpassed the maximum contamination level set by the US environmental protection agency (USEPA). Humans' annual mean exposure dose rates of various age groups were calculated for the estimated lifetime cancer risk (ELCR) and non-cancer risks. The total annual mean exposure doses from 222Rn in water (EwTotal) values were (187 ± 3.80, 265 ± 1.84, and 22.2 ± 1.02 µSv/a) for infants (143 ± 2.92, 203 ± 1.40, and 17.0 ± 0.78 µSv/a) children, and (138 ± 2.80, 196 ± 1.35, and 16.4 ± 0.76 µSv/a) adults in the Hunza district, Nagar district, and background, respectively. Among the age groups of humans, infants showed a higher risk than others. Results showed that hot springs water consumption surpassed the world health organization threshold of 100 µSv/y for chronic or non-cancer and USEPA 0.1 × 10-3 for ELCR risks. The concentration of 222Rn showed a positive correlation (> 0.68) with hot springs' water temperature and pH suggesting a common origin.

Spatial distribution of drinking and irrigation water quality indices of Ghizer River Basin, northern Pakistan.

Determining the water contamination of a river that threatens the dependent ecological community is a pillar for sustainable management. For this purpose, the present study aimed to examine the water quality of the Ghizer River Basin (GRB), Gilgit-Baltistan, northern Pakistan, for drinking and irrigation. Water samples (n = 55) were collected from the GRB and analyzed for physicochemical parameters. Water basic parameters and anions were measured using the multi-parameter analyzer (CONSORT 6030, Belgium) and cations by the atomic absorption spectrophotometer (AAS, AAnalyst 700, PerkinElmer, USA). Physiochemical parameters such as pH, electrical conductivity (EC), total dissolved solids (TDS), iodide (I), chloride (Cl), fluoride (F), nitrate (NO3), sulfate (SO4), bicarbonate (HCO3), turbidity, calcium (Ca), magnesium (Mg), potassium (K), and sodium (Na) were noted to be within the drinking water permissible limits set by the World Health Organization (WHO). However, pH and turbidity surpassed their respective limits in 2% and 48% of water samples, respectively. Samples were assessed for water quality index (WQI) and irrigation water quality (IWQ) indices. The WQI values for most samples in the GRB were noted in the excellent (38.2%), good (58.2%), and poor (3.6%) categories. Similarly, most IWQ indices revealed that water is suitable and recommended for irrigation. Gibbs plots showed that most water samples in the GRB were noted in the precipitation dominance zone. The piper plot revealed the calcium-chloride (Ca-Cl) dominant hydrochemical facies.

Evaluation of heavy metals in water and sediments, pollution, and risk indices of Naltar Lakes, Pakistan.

This study examined the physicochemical parameters of water and sediments in the Naltar Lakes, northern Pakistan. Water and sediments were sampled and analyzed for physicochemical parameters. Heavy metals such as iron (Fe, 11% and 12%), nickel (Ni, 100% and 88%), chromium (Cr, 22% and 12%), and arsenic (As, 0% and 12%) of sampling sites had surpassed the threshold of drinking water set by world health organization (WHO) in the Naltar Lake I (Naltar I) and Naltar Lake II (Naltar II), respectively. Water quality parameters were evaluated for the drinking and irrigation water quality indices (WQI). Drinking WQI values were found within the excellent category for Naltar I and Naltar II, except for the 6% of sampling sites observed in the good category. Toxic parameter concentrations were used for the risk indices, which revealed the highest average daily dose (ADD) values of 138 µg/kg-day and hazard quotient (HQ) 1.8 for children through nitrate (NO3) and As consumption in drinking water from the Naltar I and Naltar II, respectively. Water of the Naltar Lakes were characterized by rock weathering dominance. Heavy metal concentrations of sediments showed a moderate level of contamination that poses a low risk to the Naltar Lake ecosystem.

Heavy metal(loid)s contamination and potential risk assessment via groundwater consumption in the district of Hangu, Pakistan.

This study examined the concentration of heavy metal(loid)s (HM) in groundwater and associated health risks in the Hangu District, Pakistan. Seventy-one groundwater samples were selected from various sources to determine the concentration of twelve HM using the ICP-MS. The average concentrations of HM in groundwater were observed within acceptable guidelines proposed by the World Health Organization (WHO). Similarly, the groundwater of the study area based on the HM contamination index results was noted as an excellent group. Generally, the chronic daily intake (CDI) values for both adults and children were observed in the sequence of Fe > Zn > Ni > Mn > Cu > Sb > Cr > Mo > As > Pb > Co > Cd. The highest hazard quotient was computed for children through groundwater from the tube well. Moreover, both carcinogenic and non-carcinogenic hazards of groundwater were observed in the order of tube well > dug well > spring > bore well. The present study suggests that children were more susceptible to health risks than adults.

Heavy metal(loid)s contaminations in soils of Pakistan: a review for the evaluation of human and ecological risks assessment and spatial distribution.

Heavy metal(loid)s (HM) contaminations in the soil poses threats to the human and ecological community due to their bioaccumulation, toxicity, and persistent nature in the ecosystem. This review was designed to know about the HM contamination in soils, ecological risk, distribution, and potential health risks. Soil HM concentrations published in the last 30 years were collected from Springer, Science Direct, Willey, Mendeley, ResearchGate, Google Scholar, etc. HM concentrations were used for the geo-accumulation index (Igeo), contamination factor, as well as integrated indices such as spatial distribution of ecological risk index. Similarly, the Igeo pattern was observed in Sindh > Baluchistan > Punjab > Khyber Pakhtunkhwa > Gilgit-Baltistan > Islamabad. Moreover, the high ecological risk mean values ranged (160 < ERI < 320) due to cadmium (Cd) was exhibited in the Punjab and Khyber Pakhtunkhwa provinces and Islamabad. Non-carcinogenic risk like hazard quotient was found higher for children (1.59) of Punjab due to arsenic (As) ingestion, whereas the lower risk was observed due to Zn (2.5E-08) for adults of Punjab province via inhalation pathway. Similarly, the health index (HI) from exposure to As (1.61) in soil was higher than the rest of the HM. Moreover, cancerous risk was determined and found in the tolerable range (10-4-10-6). This study recommended that HM contaminants in the soil need to be monitored on regular basis, especially in Baluchistan, Gilgit-Baltistan, and Sindh provinces.

Stress ulcer prophylaxis for critically ill children: routine use needs to be re-examined.

INTRODUCTION: Stress ulcer prophylaxis (SUP) is commonly used in Paediatric Intensive Care Units (PICUs). However, strong evidence for this practice is lacking and there is a dire need for paediatric randomized controlled trials (RCTs). Our aim was to assess the usefulness of SUP with omeprazole in critically ill children. PATIENTS AND METHODS: We conducted a randomized, controlled open-label trial, including 144 children admitted into a PICU with a paediatric Sequential Organ Failure Assessment (pSOFA) score of less than 16. We randomly allocated patients to SUP with omeprazole or no SUP. The primary outcome was development of upper gastrointestinal bleeding or nosocomial infection. RESULTS: The incidence of gastrointestinal bleeding was 27.1%, but clinically significant bleeding developed in only 5.6% of patients. We did not find a significant difference in the incidence of bleeding between the prophylaxis and control groups (27.8% vs 26.4%; P = .85). We also did not find a significant difference between the groups in the incidence of ventilator-associated pneumonia (VAP) (9.6% vs 8.3%; P = .77). The incidence of central line-associated bloodstream infection (CLABSI) was higher in the prophylaxis group compared to the control group (30.6% vs 12.5%; P = .014). None of the patients developed Clostridium difficile-associated diarrhoea. We did not find significant differences in mortality, length of PICU stay or duration of mechanical ventilation. Mechanical ventilation was an independent predictor of bleeding (OR, 6.4; 95%CI, 2.73-14.9). CONCLUSION: In PICU patients with mild to moderate organ dysfunction, omeprazole does not seem to be useful for prevention of gastrointestinal bleeding while at the same time increasing the risk of CLABSI. Thus, we recommend restricting SUP to mechanically ventilated children.

Land use and land cover modification and its impact on biodiversity and the ecosystem services in District Kurram, Pakistan / Uso del suelo y modificación de la cobertura terrestre y su impacto en la biodiversidad y los servicios de los ecosistemas en el distrito de Kurram, Pakistán

Modifications of land use and vegetation cover are proceeding faster than ever before in human history, with a considerable reduction in forest cover in biodiversity hotspots. We investigated the land use and vegetation cover changes, their impact on biodiversity in the Kurram District, Pakistan, for 27 years (1989 to 2015). Temporal satellite imagery was processed using a supervised maximum likelihood classification algorithm in ARCGIS 10.1 to elucidate information regarding land use/land cover changes,with conducted structured interviews to obtain the inhabitants' perspectives on their dependence on ecosystems in Kurram, and how their environment is changing. We found that the land under forest cover and rangeland showed a remarkable decrease over the study period. This decline in rangeland and forest cover was a result of the increased of farmland, barren land. The study area is part of a biodiversity, with important medicinal, rare and unique plant species.

Las modificaciones del uso de la tierra y la cobertura vegetal están avanzando más rápido que nunca en la historia de la humanidad, con una reducción considerable de la cobertura forestal en los puntos críticos de biodiversidad. Investigamos el uso de la tierra y los cambios en la cobertura vegetal, su impacto en la biodiversidad en el distrito de Kurram, Pakistán, durante 27 años (1989 a 2015). Las imágenes satelitales temporales se procesaron utilizando un algoritmo de clasificación de máxima verosimilitud supervisada en ARCGIS 10.1 para dilucidar información sobre los cambios en el uso del suelo/cobertura del suelo, con entrevistas estructuradas realizadas para obtener las perspectivas de los habitantes sobre su dependencia de los ecosistemas en Kurram y cómo está cambiando su entorno. Descubrimos que la tierra cubierta por bosques y pastizales mostró una disminución notable durante el período de estudio. Esta disminución en los pastizales y la cubierta forestal fue el resultado del aumento de las tierras de cultivo, tierras estériles. El área de estudio es parte de una biodiversidad, con importantes especies de plantas medicinales, raras y únicas.

Soluble urokinase plasminogen activator receptor: a novel biomarker of pediatric community-acquired and hospitalacquired pneumonia.

BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is an emerging biomarker in different clinical disorders but data in pediatric pneumonia is scarce. Our objective was to assess utility of suPAR in pediatric community-acquired and hospital-acquired pneumonia. METHODS: A prospective observational study including 120 hospitalized pneumonia patients and 55 healthy controls. Patients fell into two groups: community-acquired pneumonia (CAP) group (75 patients) and hospitalacquired pneumonia (HAP) group (45 patients). CAP severity scores were calculated, including Predisposition, Insult, Response, Organ dysfunction modified (PIROm) score and Pediatric Respiratory Severity (PRESS) Score. suPAR was measured to CAP patients on admission and to HAP patients on the day of pneumonia diagnosis. suPAR was also measured to controls. RESULTS: suPAR was higher among the whole patient cohort compared with controls (p < 0.001) and higher among CAP group compared with both controls (p < 0.001) and HAP group (p < 0.001). No significant difference was found between HAP and control groups. suPAR was higher among CAP patients with shock, PICU admission, mechanical ventilation, and death (p=0.013, 0.044, 0.019, 0.049 respectively). Among CAP patients, suPAR correlated with oxygen saturation, pulse rate, respiratory rate, PRESS, and PIROm. suPAR had area under Receiver Operating Characteristic Curve=0.68 for prediction of severe CAP. Among HAP group, suPAR was negatively correlated with oxygen saturation (rs=-0.31; p=0.048) and was higher among patients with shock (p=0.005) and among those with increased pediatric Sequential Organ Failure Assessment (pSOFA) score (p=0.034). CONCLUSIONS: suPAR is promising for diagnosing pediatric CAP but not HAP. suPAR predicted illness severity in both CAP and HAP but performed better in the former.

Does It Matter Where You Live? Rural-Urban Context Among Women Entrepreneurs in Pakistan.

Entrepreneurship is considered as one of the strategies for economic and regional development. In particular, women entrepreneurs engaged in different geographic locations, where their characteristics and business factors are different in each location. This study examines home-based women entrepreneurs in Pakistan in relation to their place of residence, specifically rural or urban context. Very few studies have considered place of residence as a variable affecting women's businesses at the household level. This is critical since the business context can exert a major influence on available resources and constraints that affect business viability and sustainability. Data were collected from 504 women entrepreneurs using a survey questionnaire. Descriptive statistics, chi-square test, and binary logistics regression were used to achieve the objectives of the study. The findings revealed important and significant differences based on the rural versus urban context of women entrepreneurs including home ownership, household size, the number of adult family members in the household, family financial position, business record keeping, having a bank account, and type of business. While the binary logistic regression analysis reported adult family members, family financial position, business record keeping, bank account, and beautician business were the significant predictors of the women entrepreneurs' rural-urban model. The findings offer implications for policymakers, funders, bank/financial institutions, and non-governmental organizations for increasing women's entrepreneurship, empowerment, and income equality in developing countries.

Spatial and seasonal variation of water quality indices in Gomal Zam Dam and its tributaries of south Waziristan District, Pakistan.

This study investigated the quality of water and its seasonal variation in the Gomal Zam Dam and tributaries, south Waziristan District, Pakistan. For this purpose, water samples were collected from the Gomal Zam Dam and its tributaries in the winter and summer seasons (n = 24 in each season). Water samples were analyzed and found within drinking water guidelines set by the World Health Organization (WHO), except turbidity. Water characteristics were evaluated for the water quality index (WQI) and sodium hazards. Based on WQI and sodium hazards, the water of Gomal Zam Dam and its tributaries were observed as good and in permissible levels for drinking and irrigation, respectively. The winter season has slightly poor water quality compared to the summer season due to higher contamination. Gibbs's and Piper's models showed that the water quality of Gomal Zam Dam and its tributaries was mainly characterized by the weathering of bedrocks. The studied water is classified as Na-Cl type and Mg-HCO3 types in the summer and winter seasons, respectively. Statistical analyses revealed that geogenic sources of rock weathering are the dominant factor for controlling the water quality of the area.

Potentially Harmful Elements Accumulation and Health Risk Assessment of Edible Fish Tissues Caught from the Phander Valley, Northern Pakistan.

This study investigated the concentrations of potentially harmful elements (PHE) in edible tissues of trout fish (Salmo trutta) in the Phander Valley, Northern Pakistan. For this purpose, fish were sampled from the Phander Valley (Gilgit River and Phander Lake). PHE concentrations in edible fish tissues (muscle, fins, and skin) were determined using atomic absorption spectrometry (AAS, AAnalyst 700, Perkin Elmer, USA). Among PHE, zinc (Zn) showed the highest concentration of 1097 µg/kg in the skin, followed by manganese (Mn) of 241 µg/kg in the muscle, and the lowest of 3.78 µg/kg for cadmium (Cd) in fins. The concentration of PHE in fish tissues of the study area was observed within the threshold limits set by the food and agriculture organization (FAO). PHE concentration of fish tissues was used for the calculation of chronic risk assessment using the chronic daily intake (CDI) and hazard quotient (HQ) indices. The highest CDI values were observed for Zn through fish tissue consumption in juveniles, followed by Mn, and the lowest for Cd in adults. The HQ values were observed less than 1 for adults through PHE consumption in fish tissue; however, that of juvenile surpassed the threshold limit through Cd consumption in all studied tissues and that of Pb in the muscle and skins only. Higher HQ values than the threshold limit could pose a potential chronic risk to the exposed community. Spearman's non-parametric correlation showed a varying degree of correlation among PHE in fish tissues and canonical discriminant analyses were used to differentiate the tissues based on PHE accumulation tendencies.